Comprehensive screening
Your provider reviews your full medical and psychiatric history, current medications and treatment goals to determine if ketamine is appropriate and safe for you.
Mental Health
Ketamine Therapy. A new opening.
Medically supervised ketamine therapy in Plano, TX for adults with treatment-resistant depression, anxiety, PTSD and other mood disorders that have not responded to standard care.
What is ketamine therapy?
A different mechanism. A different result.
Ketamine is an NMDA receptor antagonist that has been studied for decades for its rapid antidepressant effects. Unlike traditional antidepressants that primarily target serotonin, norepinephrine or dopamine over several weeks, ketamine works on the glutamate system — a pathway linked to mood regulation, neuroplasticity and stress response.
For adults with treatment-resistant depression, anxiety, PTSD or OCD, ketamine therapy offers a clinically supervised option when standard medications and talk therapy have not provided adequate relief. At Precision Wellness Center, every patient is screened thoroughly and treated in a calm, private, monitored environment.
Who ketamine may help
For patients who have tried standard treatments without relief.
Ketamine therapy is not a first-line treatment. It is designed for adults whose symptoms persist despite multiple medications, therapy approaches or other interventions.
- Persistent depression despite trying multiple medications
- Anxiety that interferes with daily life
- PTSD from recent or past trauma
- OCD with limited response to standard therapy
- Chronic pain affecting mood and function
- Need for rapid symptom relief under medical care
The experience
Safe, structured, supported.
In-clinic sessions
Treatments are administered in a private, monitored suite. A typical initial course includes 6 sessions over 2–3 weeks, with maintenance visits scheduled individually.
Ongoing monitoring
We track your response, adjust frequency and coordinate with your existing mental health providers so care stays connected and safe.
Integration support
Ketamine works best alongside therapy and healthy habits. We encourage continued counseling and lifestyle support during and after treatment.
The science
How ketamine works
Traditional antidepressants often take weeks to build up in your system and mainly affect monoamine neurotransmitters. Ketamine acts on a different target: the NMDA receptor and the broader glutamate system.
This mechanism is believed to promote neuroplasticity — the brain's ability to form new connections and pathways. For many patients, this translates into faster symptom relief and a window where therapy, lifestyle changes and other supports can take hold more effectively.
Research continues, but clinical studies have consistently shown that ketamine can produce rapid reductions in suicidal ideation and depressive symptoms for some individuals — making it a valuable option when time and safety matter.
Safety first
Not everyone is a candidate. We will tell you honestly.
Your safety is the foundation of every treatment decision. Before beginning ketamine therapy, we complete a full medical and psychiatric evaluation and review all medications and supplements.
- Uncontrolled high blood pressure
- Certain heart conditions
- Active psychosis or mania
- Untreated substance use disorder
- Specific medication interactions
- Pregnancy or breastfeeding
If ketamine is not appropriate for you, we will help identify alternative options and coordinate with your mental health providers.
Questions & answers
Ketamine therapy FAQs
Ketamine therapy is used off-label in clinical settings to help adults with treatment-resistant depression, anxiety, PTSD, OCD and certain chronic pain conditions. It is typically considered when standard medications and therapy have not provided enough relief.
Many patients report noticeable improvement within hours to days after their first or second session, though individual response varies. A full course of treatment and maintenance sessions often produce the most lasting benefits.
When administered by trained medical providers in a controlled setting, ketamine is generally safe for carefully screened patients. We monitor vital signs throughout each session and review your full health history beforehand to reduce risks.
During treatment you may feel deeply relaxed, detached from your body, or experience mild perceptual changes such as altered sense of time or visual softness. These effects typically fade within an hour after the session ends.
A common initial protocol includes 6 sessions over 2–3 weeks. After that, maintenance sessions are scheduled based on how you respond. Some patients need booster treatments every few weeks; others go longer between visits.
Ketamine may not be appropriate for people with uncontrolled high blood pressure, certain heart conditions, active psychosis, untreated substance use disorders, or those taking medications that interact dangerously. A full screening determines eligibility.
You do not need a formal referral, but we do require documentation or confirmation of your diagnosis and treatment history. We may coordinate with your psychiatrist or therapist to ensure ketamine fits into your broader care plan.
Not necessarily. Many patients continue their existing medications and therapy while receiving ketamine. Our providers will review your regimen and coordinate care with your mental health team.
Ready to explore ketamine therapy?
If you or someone you love has been struggling with depression, anxiety or PTSD that has not responded to standard treatment, we invite you to schedule a confidential consultation at our Plano clinic.
Book a ketamine consultation